Liesegang rings in inflammatory breast lesions

We present two examples of Liesegang rings occurring in association with duct ectasia. Liesegang rings are a rare phenomenon usually found in association with cystic or inflammatory lesions, and may be mistaken for parasites. The first patient, a 52 year old woman, had a radiological code 4 mass lesion on screening mammography. Needle core biopsy (NCB) showed breast tissue infiltrated by sheets of single cells, with abundant foamy cytoplasm and slightly eccentric nuclei. Cytological atypia was minimal and there was no significant mitotic activity. The cells were admixed with lymphocytes, plasma cells, and neutrophil polymorphs. Immunohistochemical studies showed that the lesional cells were strongly CD68 positive and cytokeratin negative, confirming the haematoxylin and eosin impression of an inflammatory process, and excluding histiocytoid carcinoma. The …