Do we know everything about anthracyclines in the adjuvant treatment of breast cancer
2010
Breast cancer is one of the most important global health problems. Over the last years introduction of
screening mammography and increased efficacy of adjuvant therapies resulted in the reduction of mortality
in this malignancy. Many patients with breast cancer have indications for adjuvant radiotherapy and
hormonotherapy, however optimal schedules of combining these two modalities remain controversial.
In clinical practice typically radiotherapy and hormonotherapy are used both sequentially and concomitantly.
Similarly, the most effective and safe strategies for combining radiotherapy and targeted therapies
remain to be developed. It is expected that further preclinical and clinical studies, as well as rapid development
of molecular oncology will contribute to better selection of patients for particular therapeutic strategies
and their optimization.
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