Vascular endothelial growth factor C promotes cervical cancer metastasis via up-regulation and activation of RhoA/ROCK-2/moesin cascade
2010
Background
The elevated expression of vascular endothelial growth factor C (VEGF-C) is correlated with clinical cervical cancer metastasis and patient survival, which is interpreted by VEGF-C functions to stimulate angiogenesis and lymphatic genesis. However, the direct impact of VEGF-C on cervical cancer cell motility remains largely unknown.
Keywords:
- RHOA
- Cancer research
- Pathology
- Vascular endothelial growth factor C
- Angiogenesis
- Vascular endothelial growth factor A
- Moesin
- Cervical intraepithelial neoplasia
- Vascular endothelial growth factor
- Medicine
- Cell biology
- Vascular endothelial growth factor B
- actin cytoskeleton
- Rho-associated protein kinase
- Metastasis
- Biology
- Correction
- Source
- Cite
- Save
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