Clinical relations between chronic thyroiditis and aphthous stomatitis

In this study, 643 patients with thyroid disease were analized and there were 22 cases with aphthous stomatitis (3. 5%) found. 16 aphthous stomatitis (6. 8%) were found in 234 chronic thyroiditis and 3 aphthous stomatitis were found in 258 thyroid tumor cases (thyroid cancer 150 cases and 108 benign tumor cases). Others were 87 simple goiter with 3 aphthous stomatitis, 38 hyperthyroidism, 11 hypothyroidism and 6 others.Aphthous stomatitis with chronic thyroiditis was found more frequently than aphthous stomatitis with thyroid tumor (p<0. 005). Aphthous stomatitis are alleged to occure frequently in patients with chronic thyroiditis. Thyroid sicca is very effective for aphthous stomatitis with chronic thyroiditis (the effective rate is 87. 5%).