PD-1 Blockade in Mediastinal Gray-Zone Lymphoma

Christopher Melani,Ajay Major,Jeffrey Schowinsky,Mark Roschewski,Stefania Pittaluga,Elaine S. Jaffe,Svetlana Pack,Zied Abdullaev,Mark A. Ahlman,Jennifer J. Kwak,Rustain Morgan,Rachel Rabinovitch,Zenggang Pan,Bradley M. Haverkos,Jonathan A. Gutman,Daniel A. Pollyea,Clayton A. Smith,Wyndham H. Wilson,Manali Kamdar

PD-1 Blockade in Mediastinal Gray-Zone Lymphoma

2017

Christopher Melani
Ajay Major
Jeffrey Schowinsky
Mark Roschewski
Stefania Pittaluga
Elaine S. Jaffe
Svetlana Pack
Zied Abdullaev
Mark A. Ahlman
Jennifer J. Kwak
Rustain Morgan
Rachel Rabinovitch
Zenggang Pan
Bradley M. Haverkos
Jonathan A. Gutman
Daniel A. Pollyea
Clayton A. Smith
Wyndham H. Wilson
Manali Kamdar

Mediastinal gray-zone lymphoma is intermediate between classic Hodgkin’s lymphoma and primary mediastinal B-cell lymphoma. Three patients whose disease had become refractory to chemotherapy had impressive responses to PD-1 blockade.

Keywords:

Lymphoma
Refractory
Radiology
Mediastinal Gray Zone Lymphoma
Surgery
Diabetes mellitus
Disease
Medicine
Blockade
Chemotherapy
pd 1 blockade

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