Selective Molecular Transformation by Carbon-Carbon Bond Activation.

Carbon-carbon bond activation of unstrained molecules using metal compounds were reviewed.Novel transformations by carbon-carbon bond activation (i) - (iii) were proposed as targets.(i) Regioselective substituent transfer.(ii) Replacement of a carbon in the skeleton by other atoms.(iii) Stereoselective recombination of a substituent.Two transformations, (i) methyl group transfer from α-position to β-position and (ii) the replacement of a carbon by an oxygen atom, were shown using zircona and/or hafnacyclopentane derivatives in this article.