Association of high blood pressure with renal insufficiency: role of albuminuria, from NHANES, 1999-2006.

2012 
Background The relationship between hypertension and kidney disease is complicated. Clinical trials found intense blood pressure control was not associated with alterations in glomerular filtration rate (GFR) in all patients but did slow the rate of GFR decline among those with a higher baseline proteinuria. However, the underlying mechanism has been unclear.
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