GW29-e0204 Bradykinin Inhibits High-Glucose-Induced Senescence of Cardiac Progenitor Cells through the B2R/PI3K/AKT/mTOR/P53 Signal Pathways

The aim of this study is to determine the mechanism of bradykinin (BK) inhibit D-glucose induced premature senescence of c-kit positive cardiac progenitor cells (CPCs). C-kit positive CPCs were cultured from C57BL/6J mouses. CPCs were exposed to 25mM D-glucose (D-Glu) with or without treatment with