The association between the 844ins68 polymorphism in the CBS gene and breast cancer

Martha Patricia Gallegos Arreola,Luis Eduardo Figuera Villanueva,Adriana Ramos-Silva,Efraín Salas González,Ana Maria Puebla–Perez,Valeria Peralta-Leal,José Elías García-Ortiz,Ingrid Patricia Dávalos Rodríguez,Guillermo M. Zúñiga-González

The association between the 844ins68 polymorphism in the CBS gene and breast cancer

2014

Martha Patricia Gallegos Arreola
Luis Eduardo Figuera Villanueva
Adriana Ramos-Silva
Efraín Salas González
Ana Maria Puebla–Perez
Valeria Peralta-Leal
José Elías García-Ortiz
Ingrid Patricia Dávalos Rodríguez
Guillermo M. Zúñiga-González

Introduction The cystathionine beta synthase (CBS) gene plays an important role in homocysteine metabolism because it catalyzes the first step of the transsulfuration pathway, during which homocysteine is converted to cystathionine. Polymorphisms of CBS have been associated with cancer.

Keywords:

Transsulfuration pathway
Breast cancer
Cancer
Diabetes mellitus
Polymorphism (computer science)
Gene
Cystathionine beta synthase
Homocysteine
Medicine
Bioinformatics
Genotype frequency
Cardiology
Internal medicine
Genotype
Endocrinology
Odds ratio

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