Boron and Methionine Status of the Rat Affects the Plasma and Bone Mineral Response to High Dietary Aluminum

Aluminum toxicity in humans with chronic renal failure has been associated with dialysis osteomalacia syndrome. Recent findings from our laboratory suggest that boron affects calcium metabolism and bone mineralization. Two experiments were done simultaneously to ascertain whether dietary boron or magnesium affects the response of rats to high dietary aluminum, and whether the response is influenced by methionine status.