Iridium-dispersed carbon paste enzyme electrodes

An highly selective first-generation glucose biosensor, based on an iridium-dispersed carbon-paste transducer, is described. The iridium-on-carbon particles provide excellent electrocatalysis for both the reduction and oxidation of hydrogen peroxide. Such unique catalytic action offers convenient biosensing of glucose at very low operating potentials, where interfering reactions are negligible. Factors influencing the electrocatalytic and biocatalytic actions are elucidated, along with the analytical performance. Implications to other oxidase-based amperometric electrodes are discussed.