A Randomized Trial of Etretinate (Tigason®) in Palmoplantar Pustulosis

50 patients with palmoplantar pustulosis (PPP) were randomized to 8 weeks of daily treatment with either oral etretinate, 1 mg/kg b.w. or placebo. Good or moderate effect was obtained in 18 of 20 patients on etretinate compared to 6 of 21 patients on placebo (p