Spectrum correction considering light source fluctuation for non-invasive blood glucose sensing
2014
The purpose of this study is to correct baseline shift in absorbance spectrums caused by light source fluctuation.
To improve quantitative evaluation performance of blood glucose level, baseline shift is corrected by multiple
scatter correction (MSC). Moreover, to increase the effect of the MSC, water vapor absorbance is subtracted, and
relative glucose absorbance are calculated by dividing with hemoglobin absorbance at 1544 [cm-1]. In order to
verify the effectiveness of the proposed spectrum correction method, light source fluctuation is simulated on the
Fourier transform infrared spectroscopy (FT-IR), and we apply the proposed method to the spectrums measured
by FT-IR. From the simulation results, the baseline shift was successfully reduced by proposed method.
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