Correlation analysis between preoperative cognitive function and negative emotion in patients with laryngocarcinoma

Objective To explore the correlation between preoperative cognitive function and anxiety and depression in patients with laryngocarcinoma. Methods Totally 42 patients with laryngocarcinoma who were hospitalized in the Department of Otorhinolaryngology Head and Neck Surgery of 2 ClassⅢ Grade A Hospitals in Shanxi Province from September 2017 to September 2018 were selected into the observation group by convenient sampling, while 40 healthy volunteers were included in the control group. They were investigated with Self-Rating Anxiety Scale (SAS) , Self-Rating Depression Scale (SDS) and Montreal Cognitive Assessment (MOCA) . Results The preoperative SAS and SDS scores of the observation group were (41.48±5.46) and (43.69±6.16) respectively, both higher than those of the control group (t=4.189, 6.234; P<0.01) ; the preoperative MOCA score of the observation group was (22.90±4.13) , lower than that of the control group (t=2.646, P<0.01) . Correlation analysis showed that the laryngocarcinoma patients' anxiety and depression were negatively correlated with their cognitive function (r=-0.750, -0.660; P<0.01) . Conclusions Compared with the healthy volunteers, the laryngocarcinoma patients are more susceptible to anxiety, depression and cognitive disorder. The severer their anxiety and depression, the poorer their overall cognitive function was. Key words: Laryngeal neoplasms; Anxiety; Depression; Cognitive function