Characterization of the safety, effectiveness and use of oral sodium phosphate.
2001
OBJECTIVE: The objective of this study was to assess the tolerability, safety and effectiveness of an oral sodium phosphate solution as a colon preparation method prior to colonoscopy, compared to a standard polyethylene glycol preparation. EXPERIMENTAL DESIGN: A cohort-based multicenter, prospective, observational clinical study was conducted. PATIENTS: Twenty-nine centers from all over Spain participated in this study, including a total of 638 patients who met all the inclusion criteria established. RESULTS: The oral sodium phosphate solution has an effectiveness and safety profile similar to the standard poliethylene glycol preparation; however, due to its dosage, it is better tolerated by patients, with a statistically significant difference between both preparations. CONCLUSIONS: Based on the effectiveness, safety and tolerability profile of oral sodium phosphate solution in patients, it can be considered the preparation of choice before colonoscopy, since it allows a fast, effective and safe bowel cleansing in patients without contraindications.
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