Synthesis of spin labelled deoxynucleotide analogues and their incorporation with terminal deoxynucleotidyl transferase into DNA

Charles R. Toppin,Ingrid Thomas,E.V. Bobst,Albert M. Bobst

Synthesis of spin labelled deoxynucleotide analogues and their incorporation with terminal deoxynucleotidyl transferase into DNA

1983

Charles R. Toppin
Ingrid Thomas
E.V. Bobst
Albert M. Bobst

Abstract The synthesis of novel spin labelled deoxynucleoside-5′-triphosphates and their enzymatic incorporation with terminal deoxynucleotidyl transferase into DNA are described.

Keywords:

Enzyme
Purine nucleoside phosphorylase
Nucleic acid
TUNEL assay
DNA
Biochemistry
Electron paramagnetic resonance
Spin-½
Terminal deoxynucleotidyl transferase
Chemistry
Stereochemistry

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