Méthémoglobinémie après application de crème Emla ® chez un enfant : circonstances et conséquences d'un surdosage Methaemoglobinaemia in a child treated with Emla ® cream: Circumstances and consequences of overdose

SummaryBackground. „ Emla ® cream, a mixture of two local anaesthetics(prilocaine2.5%, lidocaine2.5%) hasa goodbene“t-riskpro“le. However, methaemoglobinaemiacan occur, especiallywhen the creamisappliedin excessiveamountsor overlongperiods.Patients and methods.„ The authorsreport a caseof seizureand respiratorydisturbances(MetHb=20.1%) after excessiveapplicationof Emla ® (30g) for curettageof molluscumconta-giosum in a younggirlwith eczema.Thepatientsclinicalconditionimprovedafter withdrawalof the creamandadministrationof methyleneblue, andshereturnedhomeondaytwo.Discussion. „ Thisnewcaseof methaemoglobinaemiain a childfollowingapplicationof Emla ® cream highlightsthe importanceof strict compliancewith the instructionsfor use of thismedicinal product.© 2012ElsevierMassonSAS.Allrightsreserved. La creme Emla ® (prilocaine 2,5%, lidocaine2,5%), large-ment utilisee en pediatrie dansle cadre desvaccinations,est egalementindiqueedansla preparationau curetagedemolluscums contagiosum,avec un bon pro“l de tolerance[1„3] . Cependant,la survenuedune methemoglobinemieest possible,essentiellementdansdesconditionsde surdo-sage.