Abstract 17169: Endothelium-Specific Reduction in Mitochondrial ROS Induces Coronary Angiogenesis in Ischemic Myocardium via Activation of PI3k/Akt/ERG, ERK1/2, and Jag-1 Signaling

Rayane Brinck Teixeira,Melissa Pfeiffer,Catherine Karbasiafshar,Giana Blume Corssac,Nagib Ahsan,Frank W. Sellke,Ruhul Abid

Abstract 17169: Endothelium-Specific Reduction in Mitochondrial ROS Induces Coronary Angiogenesis in Ischemic Myocardium via Activation of PI3k/Akt/ERG, ERK1/2, and Jag-1 Signaling

2020

Rayane Brinck Teixeira
Melissa Pfeiffer
Catherine Karbasiafshar
Giana Blume Corssac
Nagib Ahsan
Frank W. Sellke
Ruhul Abid

Introduction: Global reduction in reactive oxygen species (ROS) failed to improve outcomes in cardiovascular disease patients. Recent reports suggest that subcellular, rather than global ROS, play ...

Keywords:

Endothelium
Cancer research
Protein kinase B
Angiogenesis
Mitochondrion
PI3K/AKT/mTOR pathway
Medicine
Reactive oxygen species
Mitochondrial ROS
Erg

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