In vivo elasticity mapping in human skin with AuT-based OCE

Using numerical and analytical models of wave propagation in mechanically anisotropic materials, we highlight the complications associated with quantitative estimates of mechanical moduli in human skin. To obtain reliable, quantitative measurements of moduli in human skin, multiple aspects of mechanical wave propagation in structures typical of skin must be considered. Using a nearly incompressible transverse isotropic (NITI) model, preliminary measurements of both shear moduli (G and μ) in healthy in vivo human skin are presented.