Reactivity of 4‐chlorobenzo[c][2,7]naphthyridines towards Pd(0) catalyzed coupling reactions and nucleophilic substitutions. aroylation by nucleophilic substitution with analogues of acyl anions
2001
Various 4-substituted benzo[c][2,7]naphthyridines were prepared from the corresponding 4-chloro derivative by Pd(0) coupling reaction or nucleophilic substitution. More particularly, 4-aroyl-benzo[e][2,7]naph-thyridines were synthesized by aroylation with arenecarbaldehydes in the presence of 1,3-dimethylimida-zolium iodide.
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