Significance of Flow Cytometric DNA Analysis from Freshly Aspirated Samples.

The procedure of aspiration biopsy cytology by fine needle aspiration (ABC) is an option in establishing definitive diagnoses for breast cancers. In this series, a needle size of 21G was considered most suitable for ABC as well as flow cytometric DNA analysis. Histograms from fresh samples aspirated by fine needle clearly delineated a sharp peak in G0G1 phases and also a better CV was obtained than with paraffin-embedded preparations.