Collagen based biological gelatin glue

The present invention relates to a gelatin biobinding agent applying isinglass based on collagen, a method to manufacture the biobinding agent, and a constant temperature injector to inject the biobinindng agent. To achieve the purpose, provided in the present invention are a biobiniding agent including collagen, isinglass, and water. The biobinding agent in accordance to the present invention is suitable for a living body, has excellent adhesion, and can even be adhered under humid environment and higher temperature than a body temperature for a long time.