Covid-19 Gastrointestinal symptoms are not a secondary clinical manifestation: the Italian experience

After December 2019 outbreak in China, the novel Coronavirus infection has quickly overflowed worldwide and now considered the world public health crisis and the world breaking new. At May 2020 a total of 104291 laboratory-confirmed cases had been documented in Italy and Lombardy is the Northern Italian Region that major recorder to Covid-19 cases (over 62000 cases) [Ministry of Health, Civil Protection Department , daily notice].In very recent work we showed that of 10% patients had GS symptoms, confirming the rate described in a Chinese cohortsWe demonstrated that GS symptoms presented on 4.9 days before hospital admission. Also we showed that the GS range onset is very wide with up to 20 days before admission, confirming that GS could be the first signal of Covid-19 infectionOur data also confirm the importance of including GS symptoms among the spectrum of Covid-19 features, to take early diagnosis and appropriate treatments, even in patients without respiratory symptoms.