Effect of Vitamin E on Metabolism of Uremic Low Density Lipoproteins in Human Monocyte-Derived Macrophage

In vivo malondialdehyde (MDA) rich low density lipoproteins (LDL) obtained from hemodialysis (HD)-patients may undergo more degradation than native LDL (n-LDL) obtained from healthy controls in human monocyte-derived macrophage. Vitamin E treatment reduced MDA in LDL and suppressed degradation in macrophage.