Enterovirus Infections in Early Childhood and the Risk of Atopic Disease—A Nested Case-Control Study

L Korhonen, A Kondrashova, S Tauriainen. Clin Exp Allergy. 2013;43(6):625–632 The goal of this study was to assess the relationship between enterovirus infections in the first 2 years of life and atopic diseases. It also studied the importance of different enterovirus serotypes in atopic diseases. The study population was derived from the Finnish DIPP (Diabetes Prediction and Prevention) Study. Newborn infants with HLA-DQB1 risk alleles had clinic visits every 3 to 6 months for the first 2 years of life and at subsequent intervals of 6 to 12 months. At each visit, children had a comprehensive history and physical examination performed and a venous blood sample obtained. …