A Case of Tracheal Tuberculosis with Hypopharyngeal Carcinoma.

2000 
We report a case of tracheal tuberculosis with hypopharyngeal carcinoma.A 77-year-old man complained of a right neck mass, and an open biopsy was performed. The biopsy specimens revealed a squamous cell carcinoma. At that time, laryngeal, pharyngeal, esophageal and gastric tumors were not found by fiberscopy, but chest CT revealed mediastinal lymphadenopathy. Three months later, a hypopharyngeal carcinoma, tracheal telangiectasia and tracheal granulation were found by bronchofiberscopy, and the biopsy specimen of tracheal granulation showed epithelioid cells, necrosis, lymphocytic invasion and giant cells. He was diagnosed with tracheal tuberculosis and treated with INH and RFP. Furthermore, radiotherapy was employed for the hypopharyngeal carcinoma and cervical metastasis.A bronchoscopic examination 3 months after treatment revealed reduced tracheal granulation and no hypopharyngeal tumor or tracheal telangiectasia. However, the hypopharyngeal carcinoma recurred and the patient died due to a rupture of the carotid artery with carcinoma invasion. An autopsy showed that the tuberculous lesion had disappeared.
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