Glycaemic variability and oxidative stress in children, with type 1 diabetes attending a summer camp ,

Objective: To assess glycaemic variability, oxidative stress and their relationship in children and adolescents with type 1 diabetes (T1DM) attending a summer camp. Patients and methods: Cross-sectional study that included 54 children and adolescents with T1DM aged 7---16, attending a 7-day summer camp. Sociodemographic information, clinical data, and blood glucose values measured using an Accu-Chek Nano ® glucose metre were recorded. Glucose variability markers (standard deviation [SD], low blood glucose index [LBGI], high blood glucose index [HBGI], mean amplitude of glyacemic excursions [MAGE] and mean of daily differences [MODD]) were calculated. Oxidative stress was assessed by the measurement of 8-iso-prostaglandin F2 alpha (PGF2�) in a 24-h urine sample collected at the end of the camp in 14 children.