Microcirculation Model for Invasive Animal Monitoring

Long lasting success on complex surgical research models depends on meticulous surgery, proper handling of the animal all through the treatment and the careful observation of vital signs. Multiple intravascular catheters at multiple sites are still being used today and technique is named “invasive monitoring”. Modern invasive techniques measures mean arterial pressure, PaO2, PaCO2 a central venous pressure (CVP) values. Cannulation procedures give important information regarding the conditions of the animal despite having certain harmful effects at the micro-circulatory level. Thus, the process of vessel catheterization requires attention and should be reported in experimental methods. The adverse effects produced from the cannulation techniques should always be considered.