Native, Intact Glucagon-Like Peptide-1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions

Marieke Sternkopf,Magdolna Nagy,Constance C.F.M.J. Baaten,Marijke J.E. Kuijpers,Bibian M. E. Tullemans,Julia Wirth,Wendy Theelen,Tom G. Mastenbroek,Michael Lehrke,Benjamin Winnerling,Lesley Baerts,Nikolaus Marx,Ingrid De Meester,Yvonne Döring,Judith M.E.M. Cosemans,Andreas Daiber,Sebastian Steven,Joachim Jankowski,Johan W. M. Heemskerk,Heidi Noels

Native, Intact Glucagon-Like Peptide-1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions

2020

Objective: In patients with diabetes mellitus, increased platelet reactivity predicts cardiac events. Limited evidence suggests that DPP-4 (dipeptidyl peptidase 4) influences platelets via GLP-1 (g...

Keywords:

Endocrinology
Thrombosis
Dipeptidyl peptidase-4
Metabolism
Biochemistry
Glucagon-like peptide-1
Biology
Internal medicine
Diabetes mellitus
Suppressor
Thrombus
Platelet

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