Thrombotic thrombocytopenic purpura

Haemolytic anaemia, thrombocytopenia and microthrombi are hallmarks of thrombotic thrombocytopenic purpura (TTP), a rare microangiopathy that can cause severe ischaemic organ damage. The majority of cases have an autoimmune aetiology and, therefore, can be managed with immunosuppressive drugs, in addition to plasma therapy.