The intra-aortic administration of fibrinolytic enzymes in peripheral emboli experimentally induced in the aorta.

Abstract 1.1. A new technic for producing experimental arterial embolism in dogs is described. 2.2. The effect of the blood stream force on fresh and old clots is noted. 3.3. The results of the intra-arterial administration of trypsin upon the experimentally produced emboli are reported. No lysis of clots was obtained in any of these experiments. 4.4. If there is a fibrinolytic effect of trypsin on blood clots, it is not present in old clots in the aorta.