Imaging of Creutzfeldt-Jakob Disease: Imaging Patterns and Their Differential Diagnosis

The article provides an update on Creutzfeldt-Jakob disease (CJD), reviewing prion biology, subtypes of sporadic CJD, and the clinical aspects and molecular basis of this entity, with a comprehensive pictorial review of neuroimaging findings and differential diagnoses, enabling radiologists to confidently recognize this rare but invariably lethal disease.