PROGNOSTIC FACTORS FOR 30-DAYS MORTALITY IN EIGHTY YEARS AGED AND OLDER CRITICALLY ILL PATIENTS: A SINGLE CENTER RETROSPECTIVE COHORT STUDY.

INTRODUCTION Nowadays, with the rise in average life expectancy, the rate of hospitalization of the elderly population in intensive care unit (ICU) is gradually increasing. Unfortunately, there are no ideal combination of prognostic factors predicting the mortality in older patients admitted to the ICU. In the present study, we aim to determine the prognostic factors and their impacts on short-time mortality in very elderly critically ill patients. MATERIALS AND METHODS This retrospective cohort study was performed between January 2019 and February 2020. We included 133 patients aged ?80 years and hospitalized ?24 hours in the ICU. RESULTS A total of 133 critically ill patients enrolled in the present study. And, the median age of the patients was 85 (80-106) years. 30-day and overall ICU mortality rates were found 30.1% and 34.6% respectively. The patients were grouped as survivors (n=94) and non-survivors (n=39). Hospital length of stay before the ICU admission was found significantly longer in non-survivors (p=0.001). Sequential Organ Failure Assessment (SOFA) score and Acute Physiology and Chronic Health Evaluation-II (APACHE-II) score were significantly higher in those who died within 30 days (p<0.001, p<0.001). Also, blood lactate level and glucose level were respectively significantly higher in non-survivors (p<0.001, p=0.006). We found that modified Nutrition Risk in Critically Ill (mNUTRIC) score and prehospital Clinical Frailty Scale (CFS) were independent prognostic factors for the very elderly critically ill patients (HR=9.19, 95% CI=1.47-57.32, p=0.018, HR=20.16, 95% CI=2.63-54.07 p=0.004). CONCLUSION mNUTRIC score and prehospital CFS score were the most important prognostic factors in the admission of elderly patients to intensive care units.