Highly Chemoselective and Enantioselective Synthesis of 3,4-2H-Pyrindin-2-ones by an NHC-Catalyzed [3 + 3] Cyclization.

A highly chemoselective and enantioselective cyclization of γ-chloroenals and ketimines has been developed to synthesize enantiopure 3,4-2H-pyrindin-2-ones as major products. It is proposed that th...