Extractive separation method of cicadae flower immunological suppression active effective part ISP extracts

The invention discloses a method for extracting and separating cicada fungus immunosuppressive activity effective fraction ISP extract. The extract comprises total long aliphatic amino acid compounds in the cicada fungus with the main component ISP-1. ISP in the extract prepared through the method of the invention accounts for 50 percent to 95 percent by weight. The method for extracting and separating the extract can be performed in the following steps that: (1) column liquor of cicada fungus preparation; (2) separation of separation column; (3) solvent extraction; (4) extract phase comprising ISP concentration and drying, thereby obtaining the cicada fungus immunosuppressive activity effective fraction ISP extract.