Stereoselective 6-Exo Cyclization of Amidyl Radicals. An Experimental and Theoretical Study

Unsaturated primary arnidyl radicals of Z-configurations underwent efficient chemo-and stereoselective 6-exo cyclization reactions via chair-conformational transition states, leading to the predominant formations of 3,6-trans, 4,6-cis, or 5,6-trans substituted delta-lactams.