Clinical and biochemical effects of an oral leukotriene biosynthesis inhibitor (MK886) in psoriasis.

E.M.G.J. de Jong,I.M.M.J. van Vlijmen,J.C.M. Scholte,A Buntinx,B. Friedman,Wesley Tanaka,P.C.M. van de Kerkhof

Clinical and biochemical effects of an oral leukotriene biosynthesis inhibitor (MK886) in psoriasis.

1991

E.M.G.J. de Jong
I.M.M.J. van Vlijmen
J.C.M. Scholte
A Buntinx
B. Friedman
Wesley Tanaka
P.C.M. van de Kerkhof

Antipsoriatic agents have been shown to decrease skin levels of arachidonic acid and its metabolites including 12-monohydroxy-eicosatetranoic acid (12-HETE), and leukotriene B4 (LTB4

Keywords:

Skin biopsy
Leukotriene B4
Biochemistry
Psoriasis
Inflammation
Biosynthesis
Leukotriene
Arachidonic acid
Internal medicine
Chemotherapy
Biology
Endocrinology
Biomarker (medicine)

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