Bilateral adrenocortical adenomas and the pheochromocytoma syndrome

: A 43-year-old man with clinical signs of pheochromocytoma and adrenal adrenal enlargement underwent adrenalectomy. Bilateral adrenocortical adenomas accompanied by a pressure atrophy of surrounding cortex and normal adrenal medulla were found. The tumours exhibited neither immunohistochemical nor ultrastructural signs of medullar differentiation. As the clinical symptoms of pheochromocytoma slowly disappeared during the 18 month-postoperative period we consider the local tumour activity most probably responsible for the pseudopheochromocytoma symptomatology.