Preclinical evaluation of CLX-155, a novel prodrug of 5-FU for the treatment of cancer.
2020
e15614Background: CLX-155 is a novel prodrug of 5-FU, developed by adding two acetyl groups (ester bond) and a caprylic acid moiety (amide bond) to 5'-DFCR ring structure. CLX-155 is designed to ha...
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