Опыт применения генерического ламотриджина при различных формах эпилепсии (результаты фокусного наблюдения в учреждениях амбулаторной сети городского здравоохранения г. Москвы)

Current work is dedicated to analysis of treatment with generic topiramate in monoas well as in polytherapy in patients with different forms of epilepsy. Forclinical assessmentsHospital Anxiety and Depression Scale (HADS), quality of life questionnaire for patients with epilepsy (QOLIE-10) and efficacy primary assessment based on decrease in frequency of seizures and adverse events before and after switching to generic topiramate were used. As a result of focus investigation switch to Topsaver was associated with maintenance of stable therapeutic effect in more, than 80% of cases. No negative dynamics in changes of HADS and QOLIE-10 points were observed.