Comparative In Vitro Activities of Caspofungin and Micafungin, Determined Using the Method of the European Committee on Antimicrobial Susceptibility Testing, against Yeast Isolates Obtained in France in 2005-2006

Eric Dannaoui,Olivier Lortholary,Dorothée Raoux,Marie-Elisabeth Bougnoux,G. Galeazzi,C. Lawrence,D. Moissenet,I. Poilane,Damien Hoinard,Françoise Dromer

Comparative In Vitro Activities of Caspofungin and Micafungin, Determined Using the Method of the European Committee on Antimicrobial Susceptibility Testing, against Yeast Isolates Obtained in France in 2005-2006

2008

Eric Dannaoui
Olivier Lortholary
Dorothée Raoux
Marie-Elisabeth Bougnoux
G. Galeazzi
C. Lawrence
D. Moissenet
I. Poilane
Damien Hoinard
Françoise Dromer

The in vitro activities of caspofungin and micafungin against 1,038 yeast isolates have been determined. The caspofungin and micafungin MICs were lower for Candida albicans, Candida glabrata, and Candida tropicalis than for Candida parapsilosis, Candida guilliermondii, and Candida krusei. A clear correlation was seen between the MICs for the two drugs.

Keywords:

Microbiology
Biology
Candida glabrata
Virology
Candida krusei
Caspofungin
Candida parapsilosis
Candida tropicalis
Candida albicans
Micafungin
Antimicrobial
antibacterial agent

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