Characterizing COVID-19 Transmission: Incubation Period, Reproduction Rate, and Multiple-Generation Spreading
2021
Understanding the transmission process is crucial for the prevention and mitigation of COVID-19 spread This paper contributes to the COVID-19 knowledge by analyzing the incubation period, the transmission rate from close contact to infection, and the properties of multiple-generation transmission The data regarding these parameters are extracted from a detailed line-list database of 9,120 cases reported in mainland China from January 15 to February 29, 2020 The incubation period of COVID-19 has a mean, median, and mode of 7 83, 7, and 5 days, and, in 12 5% of cases, more than 14 days The number of close contacts for these cases during the incubation period and a few days before hospitalization follows a log-normal distribution, which may lead to super-spreading events The disease transmission rate from close contact roughly decreases in line with the number of close contacts with median 0 13 The average secondary cases are 2 10, 1 35, and 2 2 for the first, second, and third generations conditioned on at least one offspring However, the ratio of no further spread in the 2nd, 3rd, and 4th generations are 26 2, 93 9, and 90 7%, respectively Moreover, the conditioned reproduction number in the second generation is geometrically distributed Our findings suggest that, in order to effectively control the pandemic, prevention measures, such as social distancing, wearing masks, and isolating from close contacts, would be the most important and least costly measures © Copyright © 2021 Zhang, Zhu, Wang, Yang, Liu and Xu
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
35
References
4
Citations
NaN
KQI