2세대 약물 용출 관상동맥 스텐트 삽입 후 급성 심근 경색으로 병발한 관상동맥 연축 1예

Although several investigators have reported the coronary artery spasm after coronary artery stenting, all previous reports, coronary spasm after drug-eluting stent (DES) placement was occurred in first generation DES, such as sirolimus-eluting (Cypher®) and paclitaxel-eluting stents (Taxus®). Clinical relevance is unknown, the underlying mechanism may be delayed vascular healing due to toxic effects of the sirolimus and paclitaxel to endothelial cells (EC). The second-generation DES, such as everolimus-eluting (Xience V®) and zotarolimus-eluting stents (Endeavor®), are proving to be significantly more effective and safer than the first-generation DES.1)2) We report a patient with severe coronary artery spasm lead to myocardial infarction after second generation DES implantation at the site of detectable atherosclerotic lesion.