EFFECT OF SAFFLOR INJECTION ON THE INTESTINE ULTRASTRUCTURE CHARACTERISTICS FOLLOWING INTESTINE ISCHEMIA/REPERFUSION INJURY IN RABBITS

Aim: To explore effects of Safflor(Chinese Tradional Medicine) on the intestine ultrastructure characteristics during intestine ischemia/reperfusion injury(I/RI) in rabbits.Methods: Thirty rabbits were randomly divided into three groups : control group(group S),ischemia/ reperfusion group(group I/R) and Safflor injection group(group SI).Morphological changes of intestine ischernia/reperfusion in rabbits and the protective effects of Safflor were observed under electric telescope.Results: The intestine ultrastructure was badly injured in group I/R.Mitochondria and intestinal mucosal cells were swellen and endoplasmic reticulum expanded,however,in the SI group the ultrastructural injury of the ischemia greatly ameliorated.Conclusion: The ultrastructure injury occurred after intestine I/RI and Safflor has protective effects on the intestine ultrastructure.