Synchronous malignant tumors of the colon

According to literature the synchronous malignant tumors of the colon are 2-11% from all cases of sporadic nonhereditary colorectal cancer. This big difference in the frequency is due to variations in the accuracy of the used diagnostic methods, and also to the intentional search for associated lesions. The synchronous tumors have different biology and prognosis than solitary tumors. Investigations per formed with the methods of genetic engineering over p53 gene abnormalities strongly suggest that the great majority of synchronous colonic adenocarcinomas arise as independent neoplasms and their worsened prognosis is not a result of unusually early metastatic spread. The aim of our one-year retrospective study was to find out the frequency of these tumors towards all patients with colorectal cancer, the time for correct diagnosis (intraoperation or before the operation), and the peculiarities in the surgical tactics. We analyzed retrospectively 106 patients with colorectal cancer treated in the Department of Surgery III Medical University Plovdiv for one year period (01.06.2006-01.06.2007), 61 men (57.5%) with mean age 64+-2.5 years and 45 (42.5%) women with mean age 61+-3.1 year. Scripta Scientifica Medica 2008; 40(2): 141-143.