Effects of obesity on weight‐bearing versus weight‐supported exercise testing in patients with COPD

Obesity is associated with increased dyspnoea and reduced health status in patients with chronic obstructive pulmonary disease (COPD). Studies on the effects of obesity on exercise capacity showed divergent results. The objective of this study is to investigate the impact of obesity on weight-bearing versus weight-supported exercise tolerance in obese and normal weight patients, matched for age, gender and degree of airflow limitation.Retrospective analyses of data obtained during pre-pulmonary rehabilitation assessment in 108 obese COPD patients (OB) (age: 61.2A¢Â€Â‰A‚±A¢Â€Â‰5.3y, FEV1 : 43.2A¢Â€Â‰A‚±A¢Â€Â‰7.4%, BMI: 34.1A¢Â€Â‰A‚±A¢Â€Â‰3.9A¢Â€Â‰kg/m(2) ,) and 108 age and FEV1 -matched normal weight COPD patients (NW) (age: 61.7A¢Â€Â‰A‚±A¢Â€Â‰3.6y, FEV1 : 41.5A¢Â€Â‰A‚±A¢Â€Â‰8.4%, BMI: 22.9A¢Â€Â‰A‚±A¢Â€Â‰1.2A¢Â€Â‰kg/m(2) ,). Cardiopulmonary exercise test (CPET) and 6A¢Â€Â‰min walk test (6MWT) were performed, Borg scores for dyspnoea and leg fatigue were recorded, before and after the tests.Six-minute walk distance differed between OB (398A¢Â€Â‰A‚±A¢Â€Â‰107A¢Â€Â‰m) and NW patients (446A¢Â€Â‰A‚±A¢Â€Â‰109A¢Â€Â‰m, PA¢Â€Â‰weight-bearing exercise capacity, despite comparable exercise-related symptoms. The results of this study enhance the understanding of the impact of obesity on physical performance in COPD.