Effect of Intravenous Lidocaine on Central Venous Puncture Analgesia in Cases of Suspected or Confirmed COVID-19/ 静脉注射利多卡因对疑似及新型冠状病毒肺炎患者行中心静脉穿刺镇痛效果的影响

Objective To investigate the effect of intravenous lidocaine on central venous puncture analgesia in cases of suspected or confirmed COVID-19 Methods A total of 41 patients of suspected or confirmed COVID-19 were selected The patients were randomly divided into lidocaine group (n = 20) and control group (n = 21) In lidocaine group, 2% lidocaine 1 mg/kg was injected intravenously before puncture, and then the right internal jugular vein was punctured after 5ml local anesthesia with 1% lidocaine when the towel was disinfected, while in the control group, the same processing was completed except 0 9% normal saline was injected intravenously SBP, DBP and HR were recorded before the injection (T0), 1 min after intravenous injection (T1), local anesthesia (T2), skin expansion (T3) and at the end of puncture (T4) Analgesic effect, satisfaction score, puncture time and the incidence of dizziness, tinnitus, somnolence, perioral numbness, visual disturbance, arrhythmia and hypersensitivity were recorded Results Compared with those before the injection (T0), SBP, DBP and HR at T2 and T3 in the control group were significantly higher;SBP and DBP in lidocaine group were significantly lower than those in control group at T2 and T3 (all P < 0 05) Compared with those of the control group, analgesic effect and satisfaction degree of lidocaine group were better and higher, and the puncture time was shorter, which was statistically significant (all P < 0 05) Conclusion Intravenous lidocaine combined with local anesthesia for central venous puncture can improve analgesic effect and patients’ satisfaction, and reduce the stress response induced by puncture, which is beneficial to the prognosis of suspected or confirmed COVID-19 patients