Hamycin Treatment of Experimental Blastomycosis in Mice

SummaryHamycin, a new polyene antibiotic was effective against experimental blastomycosis in mice when injected intraperitoneally at levels between 0.01 and 0.0538 mg/mouse/day. The lowel level was only partially effective and the upper level was toxic. Hamycin was partially effective when administered orally as 0.125—5.0% by weight of food but 4.0% and 5.0% food mixtures were toxic.