Laterality and coherence analysis of Laser Doppler Flowmetry signals in bilateral Nèi guān (内关 PC 6): a potential non-invasive method to assess microdrculatory changes of people in different ages

Abstract Objective To investigate lateralization and Coherence analysis of blood perfusion in bilateral Neiguān (内关 PC 6) in different ages. Methods Healthy volunteers ( n =30) were placed in a temperature-controlled room as a resting state for 40 min. Then the blood perfusion of bilateral PC 6 were carried out using PeriFlux System 5000 for 15 minutes. Mean blood flux of every 5 minutes was calculated. Then the participants were divided into groups of young ( n =18) and the old ( n =12) as the boundary of 40 years, the asymmetry index and coherence value of bilateral PC 6 were analyzed in different group. Results The mean blood flow of the right PC 6 was significantly higher than the left PC 6 in three different epochs, the mean blood flow of right PC 6 vs left PC 6 is 9.74±3.36 vs 6.73±2.22 ( t =5.9, P t =5.11, P t =5.99, P Conclusion The blood perfusion in right PC 6 is higher than left PC 6. Coherence analysis of laser Doppler flowmetry signals in bilateral PC 6 might provide a potential non-invasive method to assess microdrculatory changes in different ages.