Comparison of Tissue Remodeling in Engineered Vascular Grafts made from Adult and Neonatal Human Dermal Fibroblasts

Source: Syedain, Z H., et al. Biomaterials 32 (2011): 714-22. This project was funded by a UROP grant from the University of MinnesotaTwin Cities and by NIH R01 HL083880. The author would like to thank the Tranquillo Lab for their generous support. • Decreasing initial fibrin concentration increases collagen production • Conditioned media increases fibrin degradation but has no significant effect on collagen production nHDF aHDF Conditioned